Founded by two Stanford-trained scientists, Mosaic is developing surgical instruments that can sense their surroundings and help physicians navigate complex anatomy.
Mosaic Intelligence Labs has emerged from stealth with $47 million in seed financing raised across two rounds led by 8VC and Fundomo.
Lingotto Innovation and Obvious Ventures also invested.
The San Francisco startup was founded by Dr. Ileana Pirozzi, CEO, and Dr. Alison "Ali" Kight Mackanic, CTO, who met during their doctoral studies at Stanford University.
Its ambition is to bring sensing, robotics and spatial intelligence into minimally invasive surgery.
Giving Surgical Instruments Their Own Senses
Modern endovascular procedures allow doctors to reach internal organs by passing flexible instruments through blood vessels.
These procedures can be less invasive than conventional surgery, but navigating the instruments remains technically demanding.
Physicians rely on X-ray images, earlier scans and physical feedback to understand where their tools are positioned.
Mosaic is developing instruments with sensors that gather information from inside the vascular system.
Combined with computation, these signals could create continuously updated three-dimensional representations of the surrounding anatomy.
The company is also building robotic controls intended to help physicians position instruments more precisely.
Teaching Machines From Surgical Experience
Mosaic's longer-term ambition is to create surgical systems that learn from repeated procedures.
By connecting information about anatomy, instrument movements and physician actions, its technology could eventually improve the ability of robotic systems to assist in complex interventions.
The company's team includes engineers with experience developing surgical technologies previously used in millions of procedures.
Those figures describe the team's prior experience, not deployments of Mosaic's own products.
A New Frontier for Medical Robotics
The investment reflects growing interest in applying physical AI to healthcare.
However, developing autonomous or semi-autonomous surgical systems requires rigorous validation, regulatory clearance and proof of clinical benefit.
Mosaic has not announced an approved commercial surgical product.
The $47 million will support development and recruitment across hardware engineering, sensing, robotics and clinical engineering.
Its biggest challenge is turning promising spatial intelligence technology into a system that improves surgical safety and consistency in real clinical environments.
Sources: company announcement (10 November); The Information; The Next Web. The amount is the total of two seed rounds, not necessarily a single raise.